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Tuesday, January 11, 2005


Applying engineering principles to curing aging (reversing aging), not just slowing aging:

SENS (Strategies for Engineered Negligible Senescence)


The Fountain of Youth
1546
Lime panel, 122,5 x 186,5 cm
Staatliche Museen, Berlin

A practical approach to developing real anti-aging medicine


SENS is a detailed plan for curing human aging. SENS is an engineering project, in the same way that medicine is a branch of engineering. The key to SENS is the appreciation that aging is best viewed as a set of progressive changes in body composition at the molecular and cellular level, caused as side-effects of essential metabolic processes. These changes are therefore best thought of as an accumulation of "damage", which becomes pathogenic above a certain threshold of abundance. The traditional gerontological approach to life extension, namely to try to slow down this accumulation of damage, is a misguided strategy, firstly because it requires us to improve biological processes that we do not adequately understand, and secondly because it can even in principle only retard aging rather than reverse it. An even more short-termist alternative is the geriatric approach, namely to try to stave off pathology in the face of accumulating damage; this is a losing battle because the continuing accumulation of damage makes pathology more and more inescapable. Instead, the engineering (SENS) strategy is not to interfere with metabolism per se, but to repair or obviate the accumulating damage and thereby indefinitely postpone the age at which it reaches pathogenic levels.


Think curing aging would be bad? Think again
What the heck is "engineered negligible senescence"? Answer
What's this nonsense about me maybe living 1000 years? Answers
Why didn't they say this on the TV last night? Answers




via TADspot

posted by DW  # 1/11/2005 03:39:00 PM


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